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Abandoning Affiliations

Source Adventurer's Guide pg. 6
A character can abandon an affiliation at any time, but she cannot replace the abandoned affiliation with a new affiliation until she has gained at least 1 character level (unless the GM decrees otherwise). Once a character has abandoned her affiliation with a group, only exceptional circumstances can allow her to regain her affiliation with that group. Abandoning an affiliation may have in-game repercussions, as members of the group may not take kindly to learning that a character has deserted them.

When a character abandons an affiliation, she cannot gain new options from that group until her affiliation with the group is restored. However, she does not lose access to options she already has, and can still gain access to affiliation options via alternative means. If a character has a prestige class or archetype associated with a group, she can continue to gain levels in that class or archetype, regardless of her current affiliation status with that group.

As an alternative way to gain more affiliation slots rather than abandoning one, a character could take the Additional Affiliations feat to expand her set of affiliations without having to sacrifice existing affiliations. And of course, if a character’s Charisma score (and thus her Charisma modifier) permanently increases, she can gain access to new affiliation slots as a result.