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All Rules in Determining Wound Points and Vigor Points

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Wound Points

Source Ultimate Combat pg. 206
Typically a creature has a number of wound points equal to twice its Constitution score. It also has a wound threshold equal to its Constitution score.

Wound points represent the amount of physical punishment a creature can take before it dies. When a creature’s wound points drop to or below its wound threshold, that creature becomes wounded. When a creature is wounded, it gains the staggered condition until it is no longer wounded. Furthermore, when a creature is wounded, if that creature takes any standard or move action on its turn, its remaining wound points are reduced by 1 and it must make a DC 10 Constitution check. If the creature fails that check, it falls unconscious.

When a creature reaches 0 or fewer wound points, it is dead.

Wound Points and Constitution Damage, Drain, and Penalties: A creature’s wound points and Constitution score are intrinsically linked. For each point of Constitution damage a creature takes, it loses 2 wound points, but this damage does not affect the creature’s wound threshold. When a creature takes a penalty to its Constitution score or its Constitution is drained, it loses 1 wound point per point of drain or per penalty for the duration of the penalty or drain. A penalty to Constitution or Constitution drain has no effect on the creature’s wound threshold.